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周军会    草莓发育生物学与种质资源创新实验室主任


邮箱:junhui.zhou@pku-iaas.edu.cn

研究方向:草莓树莓肉质果发育起始的分子机制、草莓真菌病害致病机理及植物免疫反应、园艺作物基因编辑体系的开发优化及草莓树莓种质资源创新



个人简介:

2008年9月–2015年4月,美国爱荷华州立大学 (Iowa State University),Ph.D.(博士)

2015年5月–2020年7月,美国马里兰大学帕克分校(University of Maryland, College Park),博士后

2021年3月 -,太阳成集团tyc7111cc,研究员, 草莓发育生物学与种质资源创新研究组 PI

 

主要研究领域:

       草莓是世界上最重要的小浆果之一,是现代“都市农业”的典型代表。其中我国的草莓种植面积(268万亩)和产量(500万吨)都居世界首位。草莓具有果实结构独特(假果)、生长周期相对较短(4-6月)、多年生、可以无性繁殖(匍匐茎)等特点,特别是近年来随着基因组注释的完善、转基因体系的建立和CRISPR/Cas9技术的开发,草莓逐渐发展成为研究非呼吸跃变型果实发育、匍匐茎发育的一种模式物种。悬钩子属(Rubus)树莓具有丰富的种质资源且多为二倍体,基因组较小,其果实富含SOD、鞣花酸和各种维生素,具有抗氧化、抗衰老、抗炎症、预防心血管疾病和美白皮肤等生理活性,但是在我国的普及程度仍旧相对落后。课题组以二倍体森林草莓、八倍体栽培草莓和树莓为主要研究对象,当前主要研究工作:(1). 草莓肉质果发育起始及蔷薇科果实作物肉质果发育多样性的遗传机制;(2). 草莓树莓果实品质调控的分子机制;(3). 二倍体森林草莓和树莓基因编辑体系(CRISPR/Cas9、Base editor、Prime editor)的开发及优化,八倍体栽培草莓transgene-free基因编辑体系的开发; (4). 草莓主要真菌病害的致病机理及分子抗病育种策略的开发;(5). 树莓刺发育、果核发育的分子机制;(6). 传统杂交育种与基因编辑育种结合的草莓分子设计育种。

    欢迎对课题组研究感兴趣的学生、青年学者加盟,共同发展!


代表性论文:

(*: Co-first author; #: Corresponding author)

Zhou, J. *, Li, M. *, Li, Y., Xiao, Y., Luo,X., Gao, S., Ma,Z., Sadowski,N., Timp, W., Dardick, C., Callahan, A., Mount, S., Liu, Z. (2023). Comparison of red raspberry and wild strawberry fruits reveals mechanisms of fruit type specification. Plant Physiology, kiad409. .

Ma, Z., Ma, L., Zhou, J. # (2023). Applications of CRISPR/Cas genome editing in economically important fruit crops: recent advances and future directions. Molecular Horticulture. https://molhort. biomedcentral.com/articles/10.1186/s43897-023-00049-0.

       Zhou, J., Sittmann, J., Guo, L., Xiao Y., Huang, X., Pulapaka, A., and Liu, Z. (2020). Gibberellin and auxin signaling genes RGA1 and ARF8 repress accessory fruit initiation in diploid strawberry. Plant Physiology, 185, 1059-1075.

       Zhou, J., Li, D., Wang, G., Wang F., Kunjal, M., Joldersma, D. and Liu, Z. (2019). Application and future perspective of CRISPR/Cas9 genome editing in fruit crops. Journal of Integrative Plant Biology, 62, 269-286. 

       Zhou, J., Wang, G. and Liu, Z. (2018). Efficient genome-editing of wild strawberry genes, vector development, and validation. Plant Biotechnology Journal, 16, 1868-1877. 

       Zhou, J., Peng, Z., Long, J., Sosso, D., Liu, B., Eom, J., Zhou, H., Huang, S., Cruz, C., Frommer, W., White, F. and Yang, B. (2015). Gene Targeting by the TAL Effector PthXo2 Reveals Cryptic Resistance Gene for Bacterial Blight of Rice. The Plant Journal, 82, 632-643. (引用206次)

       Antony, G. *, Zhou, J. *, Huang, S., Li, T., Liu, B., White, F., and Yang, B. (2010). Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3. The Plant Cell, 22, 3864-3876. (#equal contribution) (引用365次)

       Zhou, J., Song Y., Zhang Y. (2008). Advancement of Late Blight Resistance Genes in Potato. Biotechnology Bulletin, 5, 13-17.

       Chen, G., Xu, P., Pan, J., Li, Y., Zhou, J., Kuang, H., Lian, H. (2020). Inhibition of FvMYB10 transcriptional activity promotes color loss in strawberry fruit. Plant Science, https://doi.org/10.1016/j.plantsci.2020. 110578

       Wight, H., Zhou, J., Li, M., Hannenhalli, S., Mount, S. and Liu, Z. (2019). Draft Genome Assembly and Annotation of Red Raspberry Rubus Idaeus.  (BioRxiv: https://www.biorxiv.org/content/10.1101/ 546135v2).

       Long, J., Song, C., Yan, F., Zhou, J., Zhou, H. and Yang, B. (2018) Non-TAL Effectors from Xanthomonas oryzae pv. oryzae Suppress Peptidoglycan-Triggered MAPK Activation in Rice. Frontiers in Plant Science. 9:1857. https://doi: 10.3389/fpls.2018.01857.

       Li T., Huang S., Zhou J., Yang B. (2013). Designer TAL Effectors Induce Disease Susceptibility and Resistance to Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant, 6, 781-789.

       Song Y., Zhou, J., Zhang Y. (2007). Advancement of Tissue-specific Promoter in Plants. Biotechnology Bulletin, 6, 21-24.


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